- A3RI: UW Antarctic Astronomy and Astrophysics Research Institute
- AMANDA: Antarctic Muon And Neutrino Detector Array
- AN-8: Fuel (Also JP-8)
- ATWD: Analog Transient Wave Digitizer
- CAT: Caterpiller
- CDC: Clothing Distribution Center
- CDR: Critical Design Review
- CHC: Christchurch, New Zealand
- DAQ: Data Acquisition
- DCC: Drill Control Center
- DFL: Dark Freezer Lab
- DNF: Do Not Freeze
- DOM: Digital Optical Module
- DOME: "Old" South Pole Station
- DOMMB: DOM Main Boards
- DOR: DOM Readout
- EHWD: Enhanced Hot Water Drill
- ERD: Engineering Requirements Document
- E-Stop: Emergency Stop
- FAT: Final Acceptance Test
- FMEA: Failure Mode and Effect Analysis
- GRB: Gamma Ray Burst
- GUARD: National Air Guard - Flies the planes
- HA: Hazard Analysis
- HPP: High Pressure Pump
- ICD: Interface Control Document
- ICDS: Ice Coring and Drilling Service
- ICL: IceCube Laboratory
- IcePIC: IceCube Project Information Center
- IV&T: Inspection, Verification, & Testing
- JP-8: Fuel (Also AN-8)
- KRC: Kegonsa Research Center (Also PSL)
- MAPO: Martin Pomerantz Observatory
- MCM: McMurdo
- MDS: Mobile Drilling Structure
- MDS: Modular Deployment Structure
- MDS: UW Materials Distribution Services
- MHP: Main Heating Plant
- NPT: National Pipe Thread - Type of fitting
- NPX: South Pole Station
- NSF: National Science Foundation
- OML: Optical Module Lab
- PAP: Project Advisory Panel
- PDM: Power Distribution Module
- PDR: Preliminary Design Review
- PEP: Project Execution Plan
- PHS: Pre-Heater System
- PMP: Project Management Plan
- PMT: Photomultiplier Tube
- PSL: Physical Sciences Lab (Also KRC)
- RPS: Raytheon Polar Services Corporation
- RPSC: Raytheon Polar Services Corporation
- RWS: Rodriguez Well System
- S/W: Software
- SCOARA: Science Coordination Office for Astrophysical Research in Antarctica
- SDP: Software Development Plan
- SEMP: System Engineering Management Plan
- SES: Season Equipment Site
- SEW: Seasonal Equipment Workshop
- SSEC: Space Science and Engineering Center - A UW center
- STF: Simple Test Framework
- TeV: Terra electron Volt
- TOS: Tower Operations Site
- TOS: Tower Operations Structure
- TOW: Tower Operations Workshop
- USAP: US Antarctica Program
- VC: Verification Coordinator
- WBS: Work Breakdown Structure
- WG: Working Group
- WT1: Water Tank 1
- WT2: Water Tank 2
